Aberrant expression of miR-199a in newborns with hypoxic-ischemic encephalopathy and its diagnostic and prognostic significance when combined with S100B and …
M Li, M Ye, G Zhang - Acta Neurologica Belgica, 2021 - Springer
Neonatal hypoxic-ischemic encephalopathy (HIE) is a disorder mainly due to asphyxia
during the perinatal period, and late diagnosis leads to high mortality. In this study, the
expression of microRNA-199a (miR-199a) in HIE newborns was investigated, as well as its
clinical significance in HIE diagnosis and prognosis. Circulating levels of S100B and NSE in
HIE newborns were measured using enzyme-linked immunosorbent assay, and the
expression of miR-199a was analyzed using quantitative real-time PCR. The diagnostic …
during the perinatal period, and late diagnosis leads to high mortality. In this study, the
expression of microRNA-199a (miR-199a) in HIE newborns was investigated, as well as its
clinical significance in HIE diagnosis and prognosis. Circulating levels of S100B and NSE in
HIE newborns were measured using enzyme-linked immunosorbent assay, and the
expression of miR-199a was analyzed using quantitative real-time PCR. The diagnostic …